Molecules 2014, 19(10), 16458-16476
Published: 13 October 2014
Caffeic acid phenethyl ester (CAPE), as one of the main
active ingredients of the natural product propolis, shows the unique biological
activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune
regulation, and so on. These have attracted the attention of many researchers
to explore the compound with potent biological activities. This review aims to
summarize its bioactivities, synthetic methods and derivatives, which will be
helpful for further study and development of CAPE and its derivatives.
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