Wednesday, May 30, 2007

Newly-Isolated Propolis Component Inhibits Proliferation of Cancer Cells

Propolin H from Taiwanese Propolis Induces G1 Arrest in Human Lung Carcinoma Cells
Journal of Agricultural and Food Chemistry, 2007 May 26

Propolis, a natural product collected by honeybee, has been reported to exert a wide spectrum of biological functions. In this study, we have isolated a novel component, namely, propolin H, and investigated its effects in human carcinoma cells. Propolin H inhibited the proliferation of human lung carcinoma cell lines in MTT assay, and a significant G1 arrest was observed to occur in a dose-dependent manner at 24 h of exposure in H460 cells…

Propolin H exerts its significantly growth inhibitory effects and may have therapeutic applications.

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