Royal Jelly May Help Maintain Healthy Brain Function

AMP N1-oxide, a unique compound of royal jelly, induces neurite outgrowth from PC12 cells via signaling by protein kinase A independent of that by mitogen-activated protein kinase
Evidence-based Complementary and Alternative Medicine (eCAM), 10/29/2007

AMP N1-oxide is a unique compound not found in natural resources so far other than RJ. Therefore, it may be the molecule responsible for RJ-specific physiological actions on the CNS. Our study provides molecular-based evidence that RJ regulates neuronal functions through A2A receptor signaling enhanced by AMP N1-oxide...

Elucidation of the physiological roles of AMP N1-oxide in brain function is important to develop RJ as an evidence-based complementary and alternative medicine. Taking RJ as a source of AMP N1-oxide may be promising to maintain healthy brain functions.